Aroon Chande
Atlanta, GA 30318
H(515) 981-6868
Bmail@aroonchande.com
Íhttps://aroonchande.com
Education
Aug 2017 –
present
(In progress) Ph.D. - Bioinformatics,Georgia Institute of Technology, Atlanta, GA.
Dec 2016 Master of Science - Bioinformatics,Georgia Institute of Technology, Atlanta, GA.
May 2015 Bachelor of Science - Microbiology,University of Iowa, Iowa City, IA.
May 2013 Bachelor of Science - Biology,University of Iowa, Iowa City, IA.
Experience
May 2016 –
Present
Bioinformatics Scientist,Applied Bioinformatics Laboratory,IHRC Inc, Atlanta, GA.
http://abil.ihrc.com
{Development and maintenance of analytics platforms
{Development and maintenance of custom bioinformatics databases
{Teaching bioinformatics courses
Languages used: Bash/Perl/R/Python/C++/HTML/CSS/SQL
May 2016 –
Present
Graduate Student,Jordan Lab,Georgia Institute of Technology, Atlanta, GA.
http://jordan.biology.gatech.edu
{Studying the effects of human ancestry on disease burden in Colombia and South America
{Teaching and administrating classes in the Bioinformatics MasterâĂŹs program
{
Development of bacterial typing schemes in collaboration with the Centers for Disease Control and Prevention
Languages used: Bash/Perl/R/Python
Aug 2015 –
May 2016
Graduate Student Research,Hammer Lab,Georgia Institute of Technology, Atlanta, GA.
http://www.hammerlab.biology.gatech.edu/
{Development and maintenance of vibriocholera.com
{Vibrio cholerae NGS bioinformatic analysis
{Development of webtool for Type VI Secretion System annotation
Languages used: Bash/Perl/R/Python
Dec 2011 –
July 2015
Research Assistant,Apicella Lab,University of Iowa, Iowa City, IA.
{
Development of expression and purification protocols for NMR and x-ray crystallography study of
Haemophilus influenzae nuclease in E. coli
{
Screening and data collection on crystallized nuclease in-house and Synchrotron radiation (4.2.2 beamline
at ALS, Berkeley)
{Biological assays for protein activity, targets and pH dependence
{Biofilm, immunoassay and confocal microscopy
Languages used: Bash/Perl
May 2011 –
May 2013
Protein Crystallography Core Staff
,Carver College of Medicine, Unversity of Iowa, Iowa City, IA.
{Contracted protein purification and characterization
{User training for protein expression, purification and crystallization
{Development of custom protocols for in-house robotic liquid handlers
Languages used: Bash
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Skills
Computational
Proficient Bash, Perl, Python, R, Unix systems administration
Familiar C/C++, HTML, CSS, SQL
NGS DNA-seq, RNA-seq, microarray
’Omics Analysis of metabolomics and proteomics
Development - Bacterial typing and identification tools using NGS data
- Automated systems for bioinformatics analysis and information management
Robotics
Liquid handlers (Mosquito, TECAN, Alchemist platform), Microscopy (Rock Imager), and other
programmable robotics platforms
Wet Lab
Pathogens Collection and handling of biological samples
FPLC/HPLC Affinity column, ionic / hydrophobic chromatography
Microscopy Confocal, Light, SEM
Genetics PCR and cell line mutant development
Posters and Presentations
1. Chande, A.T.
, Rishishwar, L., Watve, S., Jordan, I.K., Hammer, B.K. (2015). Genomic analysis of Type VI
secretion systems of Vibrio cholerae. 10th International Conference on Bioinformatics, Atlanta, GA
Awards and Honors
Summer 2016
Graduate Research Award,Jordan lab, Georgia Institute of Technology, Alanta, GA.
Reclassification of Non-typeable Haemophilus spp..
Publications
13. Chande, A.T.
, Wang, L., Rishishwar, L., Conley, A.B., Norris, E.T., Valderrama-Aguirre, A., Jordan, I.K. (2018)
GlobAl Distribution of GEnetic Traits (GADGET) web server: polygenic trait scores worldwide. Nucleic Acids
Research. doi: 10.1093/nar/gky415. PubMed: 29788182
12.
Cho, C.,
Chande, A.T.
, Gakhar, L., Hunt, J., Ketterer, M. R., Apicella, M. A. (2018) Characterization of a
nontypeable Haemophilus influenzae Thermonuclease. PLoS One. doi: 10.1371/journal.pone.0197010. PubMed:
29746527
11.
Medina-Cordoba, L.K.,
Chande, A.T
, Rishishwar, L., Mayer, L.W., Mariño-Ramírez, L., Valderrama-Aguirre,
L., Valderrama-Aguirre, A., Kostka, J.E, Jordan, I.K. (2018). Genome sequences of 15 Klebsiella spp. isolates
from sugarcane fields in ColombiaâĂŹs Cauca Valley. Genome Announcements. doi: 10.1128/genomeA.00104-18.
PubMed: 29567732
10. Chande, A.T.
, Rowell, J., Rishishwar, L., Conley, A.B., Norris, E.T., Valderrama-Aguirre, A., Medina-Rivas, M.,
Jordan, I.K. (2017). Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse
Colombian populations of ChocÃş and Antioquia. Scientific Reports. doi: 10.1038/s41598-017-17380-4. PubMed:
29215035
9.
Dale, R., Grüning, B., Sjödin, A., Rowe, J., Chapman, B. A., Tomkins-Tinch, C. H., . . .
Chande, A. T.
, . . .
Köster, J. (2017). Bioconda: A sustainable and comprehensive software distribution for the life sciences. bioRxiv.
doi: 10.1101/207092
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8.
Espitia, H,
Chande, A. T.
, Jordan, I. K., Rishishwar, L. (2017). Method of sequence typing with in silico
aptamers from a Next Generation Sequencing platform. Patent Pending.
7.
Post, D. M. B., SlÃijtter, B., Schilling, B.,
Chande, A. T
., Rasmussen, J. A., Jones, B. D., . . . Apicella, M.
A. (2017). Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and
Schu S4 and Identification of Potential Subunit Vaccine Candidates. mBio, 8(5). doi: 10.1128/mBio.01592-17.
PubMed: 29018123
6.
Topaz, N., Mojib, N.,
Chande, A. T.
, Kubanek, J., & Jordan, I. K. (2017). RampDB: a web application and
database for the exploration and prediction of receptor activity modifying protein interactions. Database, 2017,
bax067-bax067. doi: 10.1093/database/bax067. PubMed: 29220456
5.
Norris, E. T., Rishishwar, L., Wang, L., Conley, A. B.,
Chande, A. T.
, Dabrowski, A. M., . . . Jordan, I. K.
(2017). Assortative mating on ancestry-variant traits in admixed Latin American populations. bioRxiv. doi:
10.1101/177634
4.
Post, D. M. B., Schilling, B., Reinders, L. M., DâĂŹSouza, A. K., Ketterer, M. R., Kiel, S. J., . . .
Chande, A.
T.
, . . . Gibson, B. W. (2017). Identification and characterization of AckA-dependent protein acetylation in
Neisseria gonorrhoeae. PLoS One, 12(6), e0179621. doi: 10.1371/journal.pone.0179621. PubMed: 28654654
3.
Watve, S. S.,
Chande, A. T.
, Rishishwar, L., MariÃśo-RamÃŋrez, L., Jordan, I. K., & Hammer, B. K.
(2016). Whole-Genome Sequences of 26 Vibrio cholerae Isolates. Genome Announcements, 4(6). doi:
10.1128/genomeA.01396-16. PubMed: 28007852
2.
Cho, C.,
Chande, A.
, Gakhar, L., Bakaletz, L. O., Jurcisek, J. A., Ketterer, M., . . . Apicella, M. A. (2015).
Role of the Nuclease of Nontypeable Haemophilus influenzae in Dispersal of Organisms from Biofilms. Infection
and Immunity, 83(3), 950-957. doi: 10.1128/iai.02601-14. PubMed: 25547799
1.
Apicella, M.A., Gakhar, L., Chande, A.T. Novel Thermonuclease from Haemophilus Influenzae and Uses Thereof
in Industry and Scientific Research. Patent Pending.
Manuscripts in preparation
1. Chande, A.T.
, Crisan, C., Rishishwar, L., Watve, S., Jordan, I.K., Hammer, B.K. Computational characterization
of Type VI Secretion Systems in Vibrio cholerae
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