Aroon Chande
Atlanta, GA 30363
H(515) 981-6868
Bmail@aroonchande.com
Íhttps://aroonchan.de
Education
Aug 2017 –
present
(In progress) Ph.D. - Bioinformatics,Georgia Institute of Technology, Atlanta, GA.
Dec 2016 Master of Science - Bioinformatics,Georgia Institute of Technology, Atlanta, GA.
May 2015 Bachelor of Science - Microbiology,University of Iowa, Iowa City, IA.
May 2013 Bachelor of Science - Biology,University of Iowa, Iowa City, IA.
Experience
May 2016 –
Present
Bioinformatics Scientist,Applied Bioinformatics Laboratory,IHRC Inc, Atlanta, GA.
http://abil.ihrc.com
{Development and maintenance of analytics platforms
{Development and maintenance of custom bioinformatics databases
{Teaching bioinformatics courses
Languages used: C++/Bash/Julia/PHP/Perl/Python/R/SQL
May 2016 –
Present
Graduate Student,Jordan Lab,Georgia Institute of Technology, Atlanta, GA.
http://jordan.biology.gatech.edu
{Studying the effects of human ancestry on disease burden in Colombia and South America
{Teaching and administrating classes in the Bioinformatics Master’s program
{
Development of bacterial typing schemes in collaboration with the Centers for Disease Control and Prevention
Languages used: Bash/Perl/Python/R/SQL/PHP/Julia/Rust
Aug 2015 –
May 2016
Graduate Student Research,Hammer Lab,Georgia Institute of Technology, Atlanta, GA.
http://www.hammerlab.biology.gatech.edu/
{Development and maintenance of vibriocholera.com
{Vibrio cholerae NGS bioinformatic analysis
{Development of webtool for Type VI Secretion System annotation
Languages used: Bash/Perl/R/Python
Dec 2011 –
July 2015
Research Assistant,Apicella Lab,University of Iowa, Iowa City, IA.
{
Development of expression and purification protocols for NMR and x-ray crystallography study of
Haemophilus influenzae nuclease in E. coli
{
Screening and data collection on crystallized nuclease in-house and Synchrotron radiation (4.2.2 beamline
at ALS, Berkeley)
{Biological assays for protein activity, targets and pH dependence
{Biofilm, immunoassay and confocal microscopy
Languages used: Bash/Perl
May 2011 –
May 2013
Protein Crystallography Core Staff
,Carver College of Medicine, Unversity of Iowa, Iowa City, IA.
{Contracted protein purification and characterization
{User training for protein expression, purification and crystallization
{Development of custom protocols for in-house robotic liquid handlers
Languages used: Bash
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Skills
Computational
Proficient Bash, Perl, Python, R, Unix systems administration
Familiar HTML/CSS, SQL
Learning Julia, Rust
NGS Whole Genome Sequencing (WGS), Whole Exome Sequences (WES), RNA-seq, microarray
’Omics Transcriptomics, metabolomics, proteomics
Development - Bacterial typing and identification tools using NGS data
- Automated systems for bioinformatics analysis and information management
Robotics
Liquid handlers (Mosquito, TECAN, Alchemist platform), Microscopy (Rock Imager), and other
programmable robotics platforms
Wet Lab
Pathogens Collection and handling of biological samples
FPLC/HPLC Affinity column, ionic / hydrophobic chromatography
Microscopy Confocal, Light, SEM
Genetics PCR and cell line mutant development
Posters and Presentations
4. Chande, A.T.
, Norris, E.T., Moreno, A.M., Nagar, S.D., Rishishwar, L., O’Neal, K., Velex, S., Montes-
Rodrigues, S., Torres, I., Medina-Rivas, M.A., Valderrama-Aguirre, A., Jordan, I.K., Gallo, J.E. (2018) Population
pharmacogenomics for precision public health in Colombia. São Paulo Advanced School on Vaccines, São Paulo,
Brazil.
3. Chande, A.T.
, Wang, L., Rishishwar, L., Conley, A.B., Norris, E.T., Valderrama-Aguirre, A., Jordan, I.K. (2018)
GlobAl Distribution of GEnetic Traits (GADGET): Exploring polygenic trait scores. The American Society of
Human Genetics, San Diego, California.
2. Chande A.T.
, Conley, A.B., Rowell, J., Rishishwar, L., Norris, E.T., Mariño-Ramírez, L., Valderrama-Aguirre, A.,
Medina-Rivas, M., Jordan, I.K. (2018) ChocoGen: Genetic ancestry and health in the Colombian Pacific. Closing
the genomics research gap, McGill University, Montreal, Canada.
1. Chande, A.T.
, Rishishwar, L., Watve, S., Jordan, I.K., Hammer, B.K. (2015). Genomic analysis of Type VI
secretion systems of Vibrio cholerae. 10th International Conference on Bioinformatics, Atlanta, GA.
Awards and Honors
Summer 2016
Graduate Research Award,Jordan lab, Georgia Institute of Technology, Alanta, GA.
Reclassification of Non-typeable Haemophilus spp..
Publications
15.
Bernardy, E.E., Petit, R.A., Moller, A.G., Blumenthal, J.A., McAdam, A.J., Priebe, G.P.,
Chande, A.T.
,
Rishishwar, L., Jordan, I.K., Read, T.D., Goldberg, J.B. (2019) Whole-Genome Sequences of Staphylococcus aureus
Isolates from Cystic Fibrosis Lung Infections. Microbiol Resour Announc 8 (3), e01564-18 doi: 10.1128/MRA.01564-
18 PubMed: 30687841
14.
Crisan C.V.*,
Chande A.T.*
, Williams K., Raghuram V., Rishishwar L., Steinbach G., Yunker P., Jordan I.K.,
Hammer B.K. (2019) Analysis of
Vibrio cholerae
genomes using a novel bioinformatic tool identifies new, active
Type VI Secretion System gene clusters. bioRxiv. doi: 10.1101/526723
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13. Chande, A.T.
, Wang, L., Rishishwar, L., Conley, A.B., Norris, E.T., Valderrama-Aguirre, A., Jordan, I.K. (2018)
GlobAl Distribution of GEnetic Traits (GADGET) web server: polygenic trait scores worldwide. Nucleic Acids
Research. doi: 10.1093/nar/gky415. PubMed: 29788182
12.
Cho, C.*,
Chande, A.T.*
, Gakhar, L., Hunt, J., Ketterer, M. R., Apicella, M. A. (2018) Characterization of a
nontypeable Haemophilus influenzae Thermonuclease. PLoS One. doi: 10.1371/journal.pone.0197010. PubMed:
29746527
11.
Medina-Cordoba, L.K.,
Chande, A.T
, Rishishwar, L., Mayer, L.W., Mariño-Ramírez, L., Valderrama-Aguirre,
L., Valderrama-Aguirre, A., Kostka, J.E, Jordan, I.K. (2018). Genome sequences of 15 Klebsiella spp. isolates
from sugarcane fields in Colombia’s Cauca Valley. Genome Announcements. doi: 10.1128/genomeA.00104-18.
PubMed: 29567732
10. Chande, A.T.
, Rowell, J., Rishishwar, L., Conley, A.B., Norris, E.T., Valderrama-Aguirre, A., Medina-Rivas, M.,
Jordan, I.K. (2017). Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse
Colombian populations of ChocÃş and Antioquia. Scientific Reports. doi: 10.1038/s41598-017-17380-4. PubMed:
29215035
9.
Dale, R., Grüning, B., Sjödin, A., Rowe, J., Chapman, B. A., Tomkins-Tinch, C. H., . . .
Chande, A. T.
, . . .
Köster, J. (2017). Bioconda: A sustainable and comprehensive software distribution for the life sciences. bioRxiv.
doi: 10.1101/207092
8.
Espitia, H,
Chande, A. T.
, Jordan, I. K., Rishishwar, L. (2017). Method of sequence typing with in silico
aptamers from a Next Generation Sequencing platform. Patent Pending.
7.
Post, D. M. B., Slütter, B., Schilling, B.,
Chande, A. T
., Rasmussen, J. A., Jones, B. D., . . . Apicella, M.
A. (2017). Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and
Schu S4 and Identification of Potential Subunit Vaccine Candidates. mBio, 8(5). doi: 10.1128/mBio.01592-17.
PubMed: 29018123
6.
Topaz, N., Mojib, N.,
Chande, A. T.
, Kubanek, J., & Jordan, I. K. (2017). RampDB: a web application and
database for the exploration and prediction of receptor activity modifying protein interactions. Database, 2017,
bax067-bax067. doi: 10.1093/database/bax067. PubMed: 29220456
5.
Norris, E. T., Rishishwar, L., Wang, L., Conley, A. B.,
Chande, A. T.
, Dabrowski, A. M., . . . Jordan, I. K.
(2017). Assortative mating on ancestry-variant traits in admixed Latin American populations. bioRxiv. doi:
10.1101/177634
4.
Post, D. M. B., Schilling, B., Reinders, L. M., D’Souza, A. K., Ketterer, M. R., Kiel, S. J., . . .
Chande, A. T.
,
. . . Gibson, B. W. (2017). Identification and characterization of AckA-dependent protein acetylation in Neisseria
gonorrhoeae. PLoS One, 12(6), e0179621. doi: 10.1371/journal.pone.0179621. PubMed: 28654654
3.
Watve, S. S.,
Chande, A. T.
, Rishishwar, L., Mariño-Ramírez, L., Jordan, I. K., & Hammer, B. K. (2016). Whole-
Genome Sequences of 26 Vibrio cholerae Isolates. Genome Announcements, 4(6). doi: 10.1128/genomeA.01396-16.
PubMed: 28007852
2.
Cho, C.*,
Chande, A.*
, Gakhar, L., Bakaletz, L. O., Jurcisek, J. A., Ketterer, M., . . . Apicella, M. A. (2015).
Role of the Nuclease of Nontypeable Haemophilus influenzae in Dispersal of Organisms from Biofilms. Infection
and Immunity, 83(3), 950-957. doi: 10.1128/iai.02601-14. PubMed: 25547799
1.
Apicella, M.A., Gakhar, L.,
Chande, A.T.
Novel Thermonuclease from Haemophilus Influenzae and Uses Thereof
in Industry and Scientific Research. Patent Pending.
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Manuscripts in preparation
1. Chande, A.T.
, Rishshwar, L., Conley, A.B.m Valderrama-Aguirre, A., Medina-Rivas, M., Jordan, I.K. (2019)
Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations. Genes.
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