Aroon Chande 1
Aroon T. Chande
PROFESSIONAL EXPERIENCE
Applied Bioinformatics Laboratory (ABiL, abil.ihrc.com), Atlanta, GA Aug 2016 - Present
Bioinformatics Scientist
Development and maintenance of grs.jordan.biology.gatech.edu
Development and maintenance of database of worldwide genetic risk scores
Teaching bioinformatics courses
School of Biological Science, Georgia Institute of Technology, Atlanta, GA
Graduate Student Research, Jordan Lab May 2016 - Present
Tasked with developing an alternate species classification scheme for Pasteurellales order
Development of a typing scheme for previously Non-typeable Haemophlius influenzae and
molecular determination of likelihood of infection in collaboration with the Centers for
Disease Control
Graduate Student Research, Hammer Lab Aug 2015 - May 2016
Development and maintenance of vibriocholera.com
Vibrio cholerae NGS bioinformatic analysis
Development of webtool for Type VI Secretion System annotation
Carver College of Medicine, University of Iowa, Iowa City, IA
Research Assistant, Apicella Lab Dec 2011 - July 2015
Development of expression and purification protocols for NMR and x-ray crystallography
study of Haemophilus influenzae nuclease in E. coli
Screening and data collection on crystallized nuclease in-house and Synchrotron radiation
(4.2.2 beamline at ALS, Berkeley)
Biological assays for protein activity, targets and pH dependence
Biofilm, immunoassay and confocal microscopy
Creation of mutants in Francisella, Haemophilus, and Neisseria
Protein Crystallography Core Staff May 2011 - May 2013
Contracted protein purification and characterization
User training for protein expression, purification and crystallization
Trained users on and maintained in-house robotic liquid handlers
Facility maintenance and interviewing and training of new staff
EDUCATION
Master of Science - Bioinformatics Dec 2016
Georgia Institute of Technology, Atlanta GA
Bachelor of Science - Microbiology Aug 2014 - May 2015
University of Iowa, Iowa City, IA
Bachelor of Science - Biology Aug 2009 - May 2013
University of Iowa, Iowa City, IA
Cell: (515)-981-6868
Email: mail@aroonchande.com
https://aroonchande.com
Aroon Chande 2
PUBLICATIONS
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Apicella, M.A., Gakhar, L., Chande, A.T. Novel Thermonuclease from Haemophilus
Influenzae and Uses Thereof in Industry and Scientific Research. Patent Pending.
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Cho, C., Chande, A., Gakhar, L., Bakaletz, L., Jurisek, J., Ketterer, M., Shao, J., Gotou, K.,
Hunt, J., O’Brien, E., Apicella, M. A. 2014. Role of the Nontypeable Haemophilus influenzae
Thermonuclease in Biofilm Remodeling. Infec. and Immunity. doi: 10.1128/IAI.02601-14
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Watve S.S., Chande A.T., Rishishwar L., Mariño-Ramírez L., Jordan I.K., Hammer B.K.
2016. Whole-genome sequences of 26 Vibrio cholerae isolates. Genome Announc
4(6):e01396-16. doi:10.1128/genomeA.01396-16.
MANUSCRIPTS IN PREPARATION
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Chande, A.T., Rishishwar, L., Watve, S., Jordan, I.K., Hammer, B.K. Characterizing novel
T6SS in environmental isolates of Vibrio cholerae.
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Post, D.M.B, Schilling, B., Reinders, L.M., D’Souza1, A.K.,, Ketterer M.R., Kiel, S.J.,
Chande, A.T., Apicella, M.A., Gibson, B.W. Identification and Characterization of AckA-
dependent Protein Acetylation in Neisseria gonorrhoeae.
POSTERS AND CONFERENCE PRESENTATIONS
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Chande, A.T., Rishishwar, L., Watve, S., Jordan, I.K., Hammer, B.K. “Genomic analysis of
Type VI secretion systems of Vibrio cholerae”. 10th International Conference on
Bioinformatics, Atlanta, GA
AWARDS AND HONORS
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Graduate Research Award, summer 2016
TECHNICAL SKILLS
Bioinformatics
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Proficient in: Perl, Bash, R, Unix systems administration
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Working knowledge: Python, C/C++, HTML/CSS
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Next generation sequencing analysis: DNA-seq, RNA-seq, microarray
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Computational and comparative genomic and transcriptome analyses
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Development of typing and identification schemes and tools
Infectious Disease Research
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Infectious disease / pathogen and human tissue sample handling.
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Protein expression and purification
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FPLC/HPLC, affinity column, ionic / hydrophobic chromatography
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Confocal and SEM microscopy.
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Fluorescent probe (FRET), ELISA, ITC and other quantification assays.
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PCR and gDNA mutant development.
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Robotic liquid handlers (Mosquito, TECAN and Alchemist platforms)